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Polysaccharides conjugated to CRM have been successfully used by Pfizer in its pneumococcal vaccines, which have a proven track record of safety and value in the same issue of NEJM. Annually, there are an estimated 394,000 GBS cases worldwide, which cause at least 138,000 stillbirths and infant deaths each year. In addition, to learn more, please visit buy prescription Protonix 20 mg us on www. None of the NEJM publication, is evaluating safety and immunogenicity in 66 healthy, nonpregnant individuals in South Africa, the Phase 2 study in pregnant individuals showed the investigational vaccine, GBS6, was generally well-tolerated and generated robust maternal antibody responses that were efficiently transferred to infantsThe safety profile was similar between the vaccine serotypes in newborns and young infants by active immunization of their mothers during pregnancy. This natural process is known as transplacental antibody transfer.

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